Searchable abstracts of presentations at key conferences in endocrinology

ea0031p216 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013

Prevalence of vitamin D insufficiency in severely obese patients seeking bariatric surgery

Smith Rachel , Batterham Rachel , Finer Nick

Background and objectives: Vitamin D deficiency and insufficiency is common in obese individuals. We aimed to determine the prevalence of vitamin D insufficiency within a cohort of severely obese individuals, exploring potential underlying associations.Methods: In a retrospective analysis of 703 patients sequentially presenting for bariatric surgery assessment, 663 had complete demographic, anthropometric, and haematological measures (vitamin D, folate, ...

ea0016s12.2 | Addicted to food? | ECE2008

Peptide YY: cure for obesity?

Batterham Rachel

Exogenous administration of the gut hormone peptide YY3-36 (PYY3-36) reduces food intake in obese humans and rodents. New lines of evidence support a role for endogenous PYY3-36 in regulating energy homeostasis. The NPY-Y2 receptor mediates the anorectic actions of PYY3-36 with rodent studies implicating the hypothalamus, vagus and brainstem as key target sites. Functional imaging in humans has confirmed that PYY3-36 activates brainstem and hypothalamic regions. The greatest e...

ea0015s64 | Young Endocrinologist prize lecture | SFEBES2008

Peptide YY: food for thought

Batterham Rachel

Complex interrelated neuronal circuits have developed in the mammalian brain to regulate many aspects of feeding behaviour. An increased understanding of how peripheral energy signals act upon these circuits to regulate food intake is essential for effective treatment of the current obesity crisis.In response to meal ingestion, several hormones are released from the gastrointestinal tract, which play a role in the regulation of energy homeostasis. Peptid...

ea0048o1 | Oral Communications | SFEEU2017

40 years of hypoglycaemia and an adrenal mass

O'Toole Sam M , Turner Ben C , Plowman P Nick , Batterham Rachel L , Drake William M

Case History: A 69-year-old gentleman was admitted having lost consciousness. This episode was preceded by typical hypoglycaemic symptoms which, in retrospect, he had experienced for four decades with increasing frequency and severity over the past year. He was hypertensive. There was no family history of endocrinopathy or diabetes.Investigations: A supervised inpatient fast was undertaken along with cross-sectional and radio-isotope imaging.<p class...

ea0048p9 | Poster Presentations | SFEEU2017

Comparison of the impact of Roux-en-Y gastric bypass and sleeve gastrectomy on 2-year post-operative glycaemic outcomes in people with type 2 diabetes: the role of weight-loss

Pucci Andrea , Makaronidis Janine , Cheung Wui-Hang , Jenkinson Andrew , Adamo Marco , Elkalaawy Mohamed , Tymoszuk Urszula , Hashemi Majid , Finer Nicholas , Batterham Rachel

Background & aims: Data comparing the effect of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) on type-2 diabetes (T2D) outcomes and the relationship between weight-loss (WL) and T2D remission are limited. Thus, we undertook a retrospective study of patients with obesity and T2D who underwent RYGB or SG and examined the relationship between 2-year (2y) post-surgery T2D and WL outcomes.Material & methods: Patients who underwent RYGB (...

ea0048oc7 | Oral Communications | SFEEU2017

Pregnancy after bariatric surgery: a single-centre retrospective cohort study

Makaronidis Janine , Pucci Andrea , Manning Sean , Cheung Wui Hang , Kingett Helen , Buckley Grainne , Kirk Amy , Carr-Rose Kayon , Tshiala Anita , Jenkinson Andrew , Elkalaawy Mohamed , Hashemi Majid , Adamo Marco , O'Brien Pat , Richens Yana , Batterham Rachel

Background: The number of women seeking bariatric surgery in order to improve their fertility is increasing. Current guidelines recommend that pregnancy should be delayed for at least 1 year post-surgery. However, there are limited data regarding pregnancy outcomes post-surgery, particularly for sleeve gastrectomy.Methods: We performed a single-centre, retrospective cohort study of pregnancies in women post-bariatric surgery. Surgical and maternity recor...